The 3D-Bioplotter® System is a versatile rapid prototyping tool for processing a great variety of biomaterials for computer-aided tissue engineering (CATE), from 3D CAD models and patient CT data to the physical 3D scaffold with a designed and defined outer form and an open inner structure. The 3D-Bioplotter® has the capacity of fabricating scaffolds using the widest range of materials of any singular rapid prototyping machine, from soft hydrogels over polymer melts up to hard ceramics and metals. Complex inner patterns can easily be designed using the 3D-Bioplotter® software to control the mechanical properties, increase cell adhesion, as well as improve the flow of nutrient media throughout the interconnecting pores of the printed implants.
- Designed for research groups new to the field of tissue engineering with few requirements in parallel material processing and automation.
- Consisting of the same basic hardware and software as the Manufacturer & Developer Series, but lacking modular capability and platform temperature control.
- Not upgradable to the same capability of the Developer or Manufacturer Series.
A simple process: A liquid, melt, paste or gel is dispensed from a material cartridge through a needle tip from a 3-axis system to create a 3D object.
One single requirement: The material to be used must, through a physical or chemical reaction, solidify.
A world of possibilities: The widest range of materials of any 3D printing technology can be processed.
Machine Properties
Filters Included
Particle
Platform Temperature Control
No
Max Heads
2
Head Temperature Range
High: 30° – 250°C (86° – 482°F)
No. of Heads Included
2
Tool Changer Type
Fixed Side-By-Side Tools
Cartridge Sizes
3-30 ml (0.1 – 1.0 fl oz)
Other Usable Modules
None
Platform Height Control
Manual
Needle Calibration
Photo Sensor
Material Calibration
Manual
External Temp. Ports
0
Included PC
Built-in PC
Build Volume (XYZ)
150 x 150 x 140 mm (5.91” x 5.91” x 5.51”)
Speed
0.1 – 150 mm/s (0.004” – 5.91”/s)
Minimum Strand Diameter
0.100 mm (0.004”) – Material Dependent
Axis Resolution (XYZ)
0.001 mm (0.00004”)
System Properties
- A new user management allows users to both share projects, materials and patterns, as well as have their own separate set of files for improved overview and security.
- Input of outer shapes through STL files.
- Multi-part and multi-material capable through the use of an automatic tool changer and multiple print heads.
- Generation of volume support structures for complex shapes.
- Database of inner patterns (user-editable) in the controlling software, avoiding requiring patterns in the STL files.
- Complex inner pattern with straight lines, zig-zag shapes and wave forms as well as hexagon shapes, including shift functions for “in between the lines” printing
- Database of materials (user-editable) with all process parameters.
- Material lifetime control to avoid scaffold fabrication with degraded materials.
- Complete control of all printing parameters (temperature, pressure, speed, etc) through the software.
- Improved surface finish of fabricated parts using randomized start position in outer contours.
- 2D Dot-Printing (Biopatterning) capability
- High-Temperature Print Head: 30° – 250°C (86° – 482°F) with reusable stainless steel cartridges.
- Needle cleaning station, with automatic cleaning before and during the print project available.
- Luer Lock needle tips, 0.1mm to 1.0mm inner diameter available.
- LOG file creation after project completion with all relevant data.
- Footprint (L x W x H): 836 x 623 x 773 mm (32.9 x 24.5 x 30.4 in.)
- Weight: About 90 kg (198 lbs)
Materials Available
A cellulose derivative for 3D printing sacrificial supports at low temperatures
A cellulose derivative for 3D printing sacrificial supports at high temperatures
A versatile thermoplastic materials for tissue engineering applications
A versatile technical-grade silicone that 3D prints objects with medium hardness
A versatile thermoplastic materials for tissue engineering applications
A versatile thermoplastic materials for tissue engineering applications
Applications
Related Printers:
3D-Bioplotter® Manufacturer Series
The 3D-Bioplotter Manufacturer Series was designed as a tool for advanced tissue engineering and also for use in a production environment. It is the most versatile and advanced of the 3D-Bioplotter options and is capable of utilizing up to 5 materials in a build as well as UV curing capabilities and both heated and cooled platform options.
Filters Included
Sterile and Particle
Platform Temperature Control
Yes (Chiller Included): -10° - 80°C (15° - 176° F)
Primary Markets
3D-Bioplotter® Developer Series
The 3D-Bioplotter® Developer Series is designed for research groups new to the field of tissue engineering, as well as for specialized use, where limited capability may still meet requirements. It consists of the same basic hardware and software as the Manufacturer Series but with reduced park position functionality. It is still capable of using multiple modular head types and an optional heated platform.
Filters Included
Particle and Sterile
Platform Temperature Control
Yes (Chiller not included): -10° - 80°C (14° - 176°F)
Primary Markets
Materials Available for the 3D-Bioplotter® Starter Series Printer
Medical grade Polycaprolactone (PCL) is a biodegradable thermoplastic polyester that is processed at high temperatures. It is suitable for both short-term and long-term use in the body (longer than 29 days) and ideal for applications such as bone regeneration, cartilage regeneration, drug release and hybrid scaffolds.
Medical grade Polycaprolactone (PCL) is a biodegradable thermoplastic polyester that is processed at high temperatures. It is suitable for both short-term and long-term use in the body (longer than 29 days) and ideal for applications such as bone regeneration, cartilage regeneration, drug release and hybrid scaffolds.
This sugar derivative can easily be processed as a melt in prolonged jobs with no measurable degradation. The material is biocompatible and cell friendly, ensuring that residue material does not negatively affect the final object’s biological properties.
LT Support RG can easily be processed as a hydrogel in short to medium long jobs. The material is biocompatible and cell friendly, ensuring that residue materials do not negatively affect the final object's biological properties.
Polycaprolactone (PCL) is one of the most versatile thermoplastic materials for Tissue Engineering Applications. With little thermal degradation, it is an excellent material for large, time-consuming parts.
This very versatile material can be used for numerous demo applications: from trying out new shapes and patterns using a cheap material; through making technical parts (e.g. gaskets); to medical device casings